Blood sugar, also known as blood glucose, is a crucial fuel that powers every cell in your body. It’s what keeps you alert, energised, and functioning throughout the day. But when blood sugar levels rise too high or fall too low, your health can be at serious risk.
In 2025, due to increasingly sedentary lifestyles, stress, poor eating habits, and rising cases of Type 2 diabetes, more people are facing unstable blood sugar levels. But what exactly is a dangerous level of blood sugar? At what point should you take immediate action?
This guide explains everything: normal ranges, warning signs, medical classifications, and what happens when levels go too far off balance. Whether you’re managing diabetes or simply monitoring your health, knowing these thresholds can prevent complications and even save lives.
Blood Glucose Basics
Glucose powers every cell. It arrives from carbohydrates in meals and from the liver’s glycogen stores when food is scarce. Hormones steer this delicate supply chain: insulin pushes glucose into tissues, while glucagon releases it back into the bloodstream. Normal plasma volume holds roughly one teaspoon of dissolved glucose at any time about four grams in an adult. This tiny quantity highlights why small diet or hormone shifts can send readings soaring or plummeting.
How the Body Regulates Sugar?
After eating, intestinal enzymes break starches into simple sugars. Rising blood glucose triggers pancreatic beta cells to squirt insulin. Muscle and fat then unlock transporters that pull sugar inside. Hours later, when levels drift downward, alpha cells release glucagon, prompting the liver to drip extra glucose back. Catecholamines, cortisol, and growth hormone add fine-tuning during stress or exercise. The arrangement works brilliantly until insulin becomes scarce, cells resist its message, or the liver overreacts.
Measuring Your Level
Two units dominate glucose testing: millimoles per litre (mmol/L) in the UK and most of the world, and milligrams per decilitre (mg/dL) in North America. Home finger-prick meters and continuous glucose monitors (CGMs) show real-time numbers, letting users spot danger before symptoms hit. A laboratory venous sample remains the gold standard for diagnosis, yet pocket devices excel for day-to-day decisions.
Normal Ranges at a Glance
- Fasting (eight hours without food): 4.0–5.5 mmol/L (72–99 mg/dL)
- Two hours after meals: below 7.8 mmol/L (140 mg/dL)
- Overnight (3 a.m. check): 4.0–7.0 mmol/L (72–126 mg/dL)
Values vary slightly by lab and individual factors, yet staying inside these bands shields organs from harm.
Too Low: Defining Hypoglycaemia
Hypoglycaemia starts below 4.0 mmol/L (72 mg/dL). Early signs include shakiness, sweating, blurred vision, and sudden hunger. Levels under 3.0 mmol/L (54 mg/dL) bring neuro-glycopenic symptoms: confusion, slurred speech, and clumsiness. A plunge below 2.8 mmol/L (50 mg/dL) can lead to seizures, loss of consciousness, or rarely, death.
Immediate Dangers of Severe Lows
The brain relies on steady glucose delivery. When supply dwindles, neurons misfire, causing personality changes, erratic behaviour, or convulsions. Severe episodes raise the risk of traffic accidents and falls. Repeated lows blunt the body’s early warning alarms, a condition called hypoglycaemia-unawareness, making future crashes harder to detect.
Too High: Defining Hyperglycaemia
Persistent readings above 11.0 mmol/L (198 mg/dL) two hours after meals point toward a brewing issue. Danger escalates once levels exceed 16.7 mmol/L (300 mg/dL). At this height, thirst, frequent urination, and fatigue set in. When blood glucose climbs past 22.2 mmol/L (400 mg/dL) and ketones appear, diabetic ketoacidosis (DKA) or hyperosmolar hyperglycaemic state (HHS) may unfold if no action is taken.
Acute Hyperglycaemic Crises
- DKA occurs mainly in type 1 diabetes when insulin is absent. Rapid fat breakdown floods the blood with acidic ketones, causing nausea, deep breathing, and abdominal pain.
- HHS strikes many older adults with type 2 diabetes. Extreme glucose pulls water from cells, thickening the blood. Dehydration, confusion, and organ failure follow.
Either crisis demands hospital care with intravenous fluids, insulin, and electrolyte correction.
Chronic Complications of High Sugar
Remaining above 10 mmol/L (180 mg/dL) most of the day stiffens blood vessels and glycosylates proteins. Over months to years this leads to retinopathy, neuropathy, kidney decline, and heart disease. Haemoglobin A1c, a three-month average, offers an early warning of lingering elevation.
Diagnostic Thresholds
- Prediabetes: fasting 5.6–6.9 mmol/L (100–125 mg/dL) or A1c 5.7–6.4 %.
- Diabetes: fasting ≥ 7.0 mmol/L (126 mg/dL) or random ≥ 11.1 mmol/L (200 mg/dL) with symptoms, or A1c ≥ 6.5 %.
Crossing these cut-offs calls for comprehensive management to block future danger.
What Drives Levels into the Red Zone?
Illness, steroids, missed tablets, carbohydrate over-load, alcohol binges, adrenal surges, late-night takeaways, or intense workouts without snack planning all tilt the balance. Menstruation, menopause, and growth spurts equally disrupt control. Understanding personal triggers empowers timely adjustments.
Warning Signs of Trouble
- Sudden shakiness, clammy skin, or pounding heart (low)
- Extreme thirst, dry mouth, or blurred sight (high)
- Fruity breath odour and rapid breathing (DKA)
- Drowsiness or personality shift (either extreme)
Treat these cues as a call to test instantly and respond.
Medicines and Dangerous Readings
Sulphonylureas and prandial insulin top the list for low-glucose risk. Newer classes such as GLP-1 receptor agonists rarely cause hypoglycaemia unless paired with older drugs. Steroids, certain antipsychotics, and high-dose beta-blockers can send levels soaring. Sharing a full medication list with clinicians helps tailor safe dosing.
Emergency Action for Lows
- Check: confirm below 4.0 mmol/L.
- Treat: swallow 15 g quick sugar—six glucose tablets or 150 ml fruit juice.
- Wait: re-test in 15 minutes.
- Repeat: if still low, take another 15 g.
- Eat: once above 4.0 mmol/L, follow with a starchy snack to stabilise.
If unconscious, a trained helper administers glucagon intramuscularly and calls emergency services.
Emergency Action for Highs
- Test ketones if glucose exceeds 16.7 mmol/L.
- Drink sugar-free fluids to prevent dehydration.
- Take correction insulin as advised by the care team.
- Re-check every two hours.
- Seek urgent care for sustained readings above 22.2 mmol/L, rising ketones, vomiting, or altered mental state.
Prevention Strategies
Balanced meals rich in fibre slow sugar absorption. Aim for half a plate of non-starchy vegetables, a quarter lean protein, and a quarter whole-grain or root vegetable. Exercise opens insulin-independent glucose channels, trimming post-meal spikes. Sleep seven hours and manage stress with breathing drills to curb hormone-induced surges.
Special Circumstances
Pregnancy
Gestational diabetes screening appears around week 24. Target ranges tighten to protect the baby: fasting below 5.3 mmol/L (95 mg/dL) and one-hour post-meal under 7.8 mmol/L (140 mg/dL).
Children
Rapid growth and play make children prone to swings. Schools should hold hypo kits and staff need training in recognition and fast treatment.
Older Adults
Kidney function, cognition, and fall risk guide targets. Slightly higher ranges may be acceptable to avoid severe lows that cause fractures.
Technology to the Rescue
CGMs provide minute-by-minute readings with arrows that show direction. Paired with smartphone apps, they send alerts before danger strikes. Closed-loop systems even adjust insulin automatically. Smart pens, cloud dashboards, and tele-clinics allow clinicians to tweak plans remotely, keeping patients safer between visits.
Quick Reference Table
Situation | mmol/L | mg/dL | Immediate Action |
---|---|---|---|
Severe low danger | < 2.8 | < 50 | Glucose gel or glucagon, call 999 |
Neuro-glycopenic low | 2.8–3.9 | 50–70 | 15 g fast-acting carbs |
Normal fasting | 4.0–5.5 | 72–99 | Maintain routine |
Safe post-meal | < 7.8 | < 140 | Monitor |
Concerning high | 11.1–16.6 | 200–299 | Extra fluids, correction insulin |
Crisis zone | ≥ 16.7 + ketones | ≥ 300 + ketones | A&E evaluation |
Must Read:
- Is Fasting Good For Diabetes?
- What is The Main Enemy of Diabetes?
- Why Controlling Blood Sugar Is Crucial for Your Health?
FAQs:
Why do I shake at 4.3 mmol/L while my friend feels fine at 3.5 mmol/L?
Personal thresholds vary. If your average runs high, a normal reading may feel like a low. Gradual target tightening restores natural alerts.
Can non-diabetics hit dangerous highs?
Yes. Severe infections, certain drugs, or genetic conditions can push glucose over 22 mmol/L. Immediate assessment is vital.
Do high-fibre carbs prevent spikes?
They slow digestion, reducing peaks, yet portion size still counts. Combine oats, legumes, and vegetables for best stability.
Is ketoacidosis possible in type 2 diabetes?
Absolutely, especially during illness or steroid use. Watch ketones whenever glucose stays above 16.7 mmol/L.
Will exercise always drop my sugar?
Aerobic movement lowers it, but intense sprints can raise it briefly due to adrenaline. Check before and after workouts to learn your pattern.
How often should I replace my meter?
Most devices stay accurate for four to five years. Update sooner if readings clash with lab results or strips become hard to source.
Final Words:
Blood sugar can swing from ally to enemy in minutes. Learn your safe bands, track trends, and carry quick carbs for lows. Use correction protocols for highs, hydrate generously, and never delay care during breathlessness, confusion, or persistent vomiting. Smart food choices, regular activity, ample sleep, and stress control all make dangerous extremes less likely.
Technological advances now alert users before a crisis, yet personal know-how remains the first line of defence. Share this guide with family, friends, or co-workers so everyone can spot warning signs and act fast. Consistent vigilance turns what once felt like a constant threat into a manageable part of daily health, letting you focus on living well rather than fearing numbers.